Mannitol

 

Class:
Osmotic diuretic.


Actions:
Decreases cellular edema, increases urinary output.


Indications:
Acute cerebral edema, blood transfusion reactions.


Contraindications:
Pulmonary edema, patients who are dehydrated, hypersensitivity to the drug.


Precautions:
Rapid administration can cause circulatory overload crystallization of the drug can occur at lower temperatures. An in-line filter should be used.


Side Effects:
Pulmonary congestion, sodium depletion, transient volume overload.


Dosage:
1.5-2.0 g/kg.


Routes:
IV.


Pediatric Dosage:
0.25-0.5 g/kg IV over 60 minutes.
 

 

Note: Feel free to discuss this medication and your experiences in administering it in an emergency or hospital based setting on our message board